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Alnylam Pharmaceuticals Employees Reviews, Feedback, Testimonials

Biotechnology (RNAi therapeutics)Cambridge, USA501-1,000 employees
4.5
2 reviews

About Alnylam Pharmaceuticals

Alnylam Pharmaceuticals is a biopharmaceutical company focused on RNA interference (RNAi) therapeutics for genetic, cardio-metabolic, and rare diseases. Headquartered in Cambridge, Massachusetts, the company develops targeted RNAi medicines designed to silence disease-causing genes. Key products and programs span treatments for hereditary ATTR amyloidosis and other genetic disorders, with a pipeline that highlights precision medicine and novel delivery technologies. The organization is research-driven and positions itself at the intersection of molecular biology and translational medicine. Employees often cite a highly collaborative lab environment, opportunities for scientific growth, and investment in professional development across R&D and regulatory functions. A unique achievement: Alnylam was central to advancing the first FDA-approved RNAi therapy, marking a milestone for the RNAi field. That heritage makes the company appealing to scientists and clinicians interested in pioneering therapeutic modalities and bench-to-bedside innovation.

Detailed Alnylam Pharmaceuticals employee reviews & experience

Employee Testimonials

Employees I spoke with and read about often describe Alnylam as a place with real scientific purpose. People who enjoy research and seeing therapies move from idea to patient tend to be happiest. Common themes in testimonials: pride in the mission, smart teammates, and strong lab and clinical support. On the flip side, some employees mention periods of high pressure during clinical readouts or regulatory work. Overall, those who value impact say working at Alnylam Pharmaceuticals feels meaningful and energizing.

Company Culture

The company culture at Alnylam Pharmaceuticals leans toward collaborative and mission-driven. There is a clear focus on RNA therapeutics and getting treatments to patients, which creates a shared sense of purpose. Teams are generally open to cross-functional work, and scientific curiosity is welcomed. That said, the culture can feel performance-oriented, especially in commercial and late-stage development functions. For people seeking a collegial, driven environment, the company culture at Alnylam Pharmaceuticals is a good match.

Work-Life Balance

Work-life balance at Alnylam Pharmaceuticals varies by role. Lab and clinical roles can demand long hours during critical experiments or trial phases. Many corporate and support teams report reasonable schedules and flexible policies, but peaks are common. If you value predictable hours, check the team and manager expectations. For those who prioritize family time or steady routines, it helps to ask about workload rhythms in interviews to understand real day-to-day expectations.

Job Security

Job security is generally stable at Alnylam, especially as the company has grown and commercialized products. However, biotech is a results-driven industry; clinical setbacks or market changes can trigger adjustments. Most employees feel secure when programs are progressing, but those tied to early-stage projects should be comfortable with inherent risk. Overall, job security is solid but not immune to the ups and downs of biotech.

Leadership and Management

Leadership at Alnylam is seen as scientifically credible and focused on long-term patient impact. Executive communication tends to emphasize data and strategy, which resonates with technically minded staff. Some employees praise leaders for transparency around milestones; others wish for more frequent company-wide updates. Management quality can vary by department, with stronger alignment in R&D and variability in newer commercial teams.

Manager Reviews

Managers are frequently described as knowledgeable and supportive, especially when they understand the science. Good managers invest in career growth and create space for experimentation. Less positive reviews point to managers who prioritize deliverables over people, especially under tight timelines. As with many companies, your immediate manager will greatly shape your experience working at Alnylam Pharmaceuticals.

Learning & Development

Learning and development opportunities are solid. There are internal seminars, cross-functional project options, and access to scientific conferences. New hires get structured onboarding, and ongoing training supports regulatory, safety, and compliance needs. If you want professional development, there are paths, but you may need to advocate for stretch assignments or external training to accelerate growth.

Opportunities for Promotions

Promotion opportunities exist and tend to follow demonstrated impact, leadership in projects, and successful program outcomes. Career ladders are clearer in established functions like R&D and manufacturing. In smaller or newer groups, progression can be slower or dependent on team expansion. Networking and visibility in cross-functional programs help when aiming for promotions.

Salary Ranges

Salaries are competitive for biotech, with stronger packages in commercial and senior scientific roles. Early-career researchers and support roles may earn market-appropriate pay, though location matters. Compensation typically reflects experience, function, and geographic region. If salary is a priority, negotiate with clear evidence of market rates and personal accomplishments.

Bonuses & Incentives

Bonuses and incentives are part of total compensation, especially for commercial and executive roles. There are performance-based bonuses and equity awards that align employees with long-term company success. Stock and equity components can be valuable if the company performs well, which many employees find motivating.

Health and Insurance Benefits

Health benefits are comprehensive, including medical, dental, and vision plans typical for mid-to-large biotech firms. There are wellness programs and support for mental health resources. Employees commonly report satisfaction with the benefits package, though specific plan details and out-of-pocket costs depend on location and plan choices.

Employee Engagement and Events

Alnylam runs employee engagement activities like town halls, science talks, and social events. There is effort to build community through volunteer days and team outings. Remote and field staff sometimes feel less connected, but virtual events and local hubs help bridge gaps. Engagement is decent, with room to increase inclusive planning for distributed teams.

Remote Work Support

Remote work support has evolved; many roles allow hybrid arrangements, but lab-based and on-site functions require physical presence. The company provides tools for collaboration, and managers often accommodate flexible schedules when possible. If remote work is critical, confirm role-specific policies during the interview.

Average Working Hours

Typical hours for office and corporate roles hover around 40-45 per week, with spikes during launches or clinical milestones. Lab and clinical staff can expect irregular hours during key experiments or trials. Average working hours are manageable most of the time but can intensify during high-priority periods.

Attrition Rate & Layoff History

Attrition has been moderate and often tied to the natural churn of biotech talent and program shifts. There have been limited public layoffs relative to some peers, and most turnover seems voluntary as employees pursue new opportunities. Still, biotech cyclicality means employees should remain aware of program-dependent risks.

Overall Company Rating

Overall rating: 4.1/5. Alnylam Pharmaceuticals scores highly for mission-driven work, scientific leadership, and competitive benefits. It can be intense during key program phases, and experiences vary by team and role. If you care about purpose, strong science, and working with bright colleagues, Alnylam is a compelling place. For those prioritizing steady hours or remote flexibility above all else, dig into role-specific expectations before accepting an offer. This rating reflects a balance of meaningful work, solid compensation, and occasional biotech-style intensity in a fast-moving environment.

Detailed Employee Ratings

3.5
Work-Life Balance
4
Compensation
4.5
Company Culture
4.5
Career Growth
4.5
Job Security

Filter Reviews

2 reviews found

Employee Reviews (2)

Read authentic experiences from current and former employees at Alnylam Pharmaceuticals

5.0

Senior Scientist, RNA Therapeutics Review

Research & DevelopmentFull-timeHybrid
July 28, 2025

What I liked

Working at Alnylam means being part of cutting-edge RNA therapeutics. The science is exciting, leadership supports growth, and benefits (health, equity, parental leave) are strong. Cross-functional collaboration with clinical and regulatory teams really helps move programs forward.

Areas for improvement

The pace can be intense around key milestones, which sometimes means long days. A few internal processes still feel bureaucratic and could be streamlined.

4.0

Territory Sales Manager Review

Commercial / SalesFull-timeRemote
March 15, 2025

What I liked

Strong product portfolio and clear mission around rare diseases. Training for field teams is thorough, and there is good data support for account planning. People are passionate and collaborative.

Areas for improvement

Sales targets can be aggressive during new launches and that impacts work-life balance. Mid-level promotion timing felt slow when I was there.